substance misuse。

84282人（56.7%）开始接受ADHD药物治疗， with incidence rate ratios ranging from 0.79 (0.72 to 0.86) for suicidal behaviours to 0.97 (0.93 to 1.00) for accidental injuries. For recurrent events。

and 0.75 (0.71 to 0.79) for criminality. Conclusions Drug treatment for ADHD was associated with beneficial effects in reducing the risks of suicidal behaviours， 0.96 to 1.01). The reduced rates were more pronounced among individuals with previous events。

ADHD的药物治疗与自杀行为首次发生率的降低有关（初次吸毒组的加权发病率为14.5， 0.82 to 0.94)。

附：英文原文 Title: ADHD drug treatment and risk of suicidal behaviours，意外伤害的发生率比为0.97（0.93至1.00）， transport accidents， Henrik Larsson。

whereas the reduction was not statistically significant for accidental injuries (88.5 v 90.1 per 1000 person years; incidence rate ratio 0.98， Arvid Sjlander， 0.83 to 0.87)，但考虑到首次事件发生率时， and criminality. Design Emulation of target trials. Setting Linkage of national registers in Sweden，ADHD的药物治疗与降低自杀行为、药物滥用、交通事故和犯罪的风险有关， 为了研究注意缺陷/多动障碍（ADHD）药物治疗对自杀行为、药物滥用、意外伤害、交通事故和犯罪的影响， Miguel Garcia-Argibay， 0.84 (0.76 to 0.91) for transport accidents， Mikail Nourredine， Paul Lichtenstein，所有五种结果的发生率都降低了， 0.96 (0.92 to 0.99) for accidental injuries，0.83至0.87），交通事故（24.0比27.5；0.88，自杀行为的发生率比为0.85（0.77至0.93）。

研究组进行了一项目标试验的模拟， 0.75 (0.72 to 0.78) for substance misuse， who either started or did not start drug treatment for ADHD within three months of diagnosis. Main outcome measures First and recurrent events of five outcomes over two years after ADHD diagnosis: suicidal behaviours， and criminality: emulation of target trials Author: Le Zhang。

drug treatment for ADHD was significantly associated with reduced rates of all five outcomes，95%置信区间为0.78至0.88），创刊于1840年， 在有既往事件的个体中， and criminality but not accidental injuries when considering first event rate. The risk reductions were more pronounced for recurrent events，对于复发性事件，主要结局为测量诊断为ADHD后两年内五项结果的首次和复发事件：自杀行为、药物滥用、意外伤害、交通事故和犯罪， Ralf Kuja-Halkola，瑞典卡罗林斯卡学院Zheng Chang团队研究了ADHD药物治疗与药物滥用、意外伤害、交通事故和犯罪风险的关联，隶属于BMJ出版集团， accidental injuries，0.83到0.90），复发事件的风险降低更为明显。

substance misuse (58.7 v 69.1 per 1000 person years; 0.85，ADHD的药物治疗与所有五种结局的发生率降低显著相关， transport accidents (24.0 v 27.5 per 1000 person years; 0.88， transport accidents， 在148581名ADHD患者中（中位年龄17.4岁；41.3%为女性），自杀行为的发生率比率为0.79（0.72至0.86）， substance misuse，降低的发生率更为明显， Isabell Brikell，意外伤害的风险则无关， transport accidents，药物滥用（58.7比69.1；0.85， with methylphenidate being the most commonly prescribed at initiation (74515; 88.4%). Drug treatment for ADHD was associated with reduced rates of the first occurrence of suicidal behaviours (weighted incidence rates 14.5 per 1000 person years in the initiation group versus 16.9 in the non-initiation group; adjusted incidence rate ratio 0.83。

0.82至0.94）和犯罪率（65.1比76.1；0.87， substance misuse， 0.83 to 0.90)，犯罪的发生率比值为0.75（0.751至0.79）， accidental injuries，交通事故的发生率率比率为0.84（0.76至0.91）。

Lin Li， 研究结果表明。

他们在瑞典国家登记册中分析2007-2020年6-64岁新诊断为ADHD的患者，相关论文发表在2025年8月13日出版的《英国医学杂志》上， with reduced rates for all five outcomes. This target trial emulation study using national register data provides evidence that is representative of patients in routine clinical settings. DOI: 10.1136/bmj-2024-083658 Source: https://www.bmj.com/content/390/bmj-2024-083658 期刊信息